Therapeutic angiogenesis is an experimental area of treatment for cardiac ischemia, which is a common symptom of coronary artery disease.  Coronary Artery Disease & Heart Attack: Every 29 seconds, an American will experience a coronary event such as a heart attack. Cardiac ischemia is usually a temporary situation in which the heart does not get enough oxygen. This lack of oxygen is often due to a blocked or obstructed coronary artery in the heart. Angiogenesis is the process by which new blood vessels are formed to supply the heart muscle with oxygen-rich blood. These new blood vessels are called collaterals.

The term “collaterals” should not be confused with the growth of the heart’s coronary arteries or the aorta. Collaterals are smaller branches of blood vessels.

Angiogenesis is a natural process that occurs during healing. The goal with therapeutic angiogenesis is to stimulate the creation of blood cells through medical intervention. By doing this, researchers hop to increase the level of oxygen-rich blood reaching damaged areas of the heart.

Although more research is necessary, some researchers are hoping that therapeutic angiogenesis may one day offer the benefits of a bypass without the open-heart surgery
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This site provides info on therapeutic angiogenesis: Center for Therapeuti Angiogenesis

See also:

Therapeutic angiogenesis in cardiovascular disease

Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells